Do you want to find the best supplement for your joint pain?

To make this decision easier, we compiled a list of the 9 best supplements that have been proven to work in 2021.

The goal is to provide you with unbiased information so that you can choose what’s right for your needs.

So without further ado, let’s get started!


The Centers for Disease Control and Prevention (CDC) has found that more than 25% of American individuals suffer from chronic joint pain in their knees, hands, elbows, shoulders, and elsewhere. These patients have typically prescribed pain relievers such as acetaminophen or nonsteroidal anti-inflammatory drugs such as ibuprofen to alleviate the symptoms. Overuse of these drugs can cause a rebound effect where the pain returns with greater intensity.

However, such medications are not good for our overall health in the long run.

Luckily, dozens of dietary supplements claim to be beneficial to joint pain and have no serious side effects associated. Below are the best 9 natural supplements approved for joint pain relief and arthralgia.

Palmitoylethanolamide (PEA) supplement

Palmitoylethanolamide, also known as PEA, is a fatty acid amide naturally occurring in all of our bodies. Research has shown that it may be vital for supporting the body’s natural pain response and aiding in recovery from injury.

PEA is experiencing a surge in popularity as a natural way to heal chronic pain and inflammation. The substance, found in the plant family of legumes, has been shown to help with conditions such as neuropathic pain, fibromyalgia, multiple sclerosis (MS), carpal tunnel syndrome, and infections of the airway.

Turmeric extract supplement (Curcumin)

Turmeric has been shown to be a reliable pain reliever, with the ability to help manage joint and osteoarthritic pain. Turmeric’s active ingredient, curcumin powder is thought to play a key role in this process. Curcumin has been proven analgesic and may also be helpful for various other types of pathological pain – so why not add turmeric powder into your diet today?

Turmeric has been shown time and again as an effective solution for managing joint or osteoarthritic pain by top researchers around the world! The active ingredient in raw turmeric powder, curcumin is thought to contribute immensely to its efficacy as a natural health supplement. Studies have also confirmed that it can provide relief from other forms of pathological chronic

Curcumin, an aromatic yellow compound, has been shown to have analgesic effects and may be useful for a variety of pathological pain conditions.  Curcumin reduces levels of inflammatory mediators involved in nociceptive pain hypersensitivity and is often formulated with palmitoylethanolamide because it provides better pain relief management.

CBD oil supplement

CBD, short for cannabidiol, is rapidly becoming a new form of natural pain relief. People looking for a safer and more natural approach to pain relief are turning to CBD oil as an alternative to pharmaceutical drugs.

CBD oil might help reduce inflammation, which in turn might relieve chronic pain. People with arthritis who tried CBD experienced noticeable relief from their chronic pain and sleep quality improved tremendously.

It seems that CBD oil can ease chronic pain by reducing inflammation. Many people suffering from arthritis reported significant improvements to their symptoms after trying CBD oil, including experiencing less pain, increased sleep quality, and anxiety reduction!

Glucosamine/chondroitin supplement

It’s no wonder that glucosamine and chondroitin have been the leading players in joint health for decades. These two supplements work to reduce pain, increase mobility, and even decrease the need for painkillers.

Devil’s claw extract supplement

Devil’s claw is a natural way to relieve pain that has been known for centuries. The plant compound harpagoside, which gives devil’s claw its medicinal properties, also helps with inflammation and relieves muscle aches.

The devil’s claw root could be the answer to all your joint problems. It has been shown in lab studies to block several pathways that cause inflammation. This active ingredient, harpagoside, is most likely what leads this plant to be so effective for arthritis. Devil’s claw trials have also proven useful for osteoarthritis patients and is reported to be more effective than ibuprofen at reducing pain and disability.

 Boswellia supplement (Boswellia acids)

Boswellia serrata, also known as Indian frankincense, is one of those dark horses in the world of anti-inflammatories. Clinical studies have shown that boswellia extracts improve pain symptoms more than a placebo in people with osteoarthritis. The Arthritis Foundation says it blocks enzymes that turn your food into molecules attacking your joints and improves pain symptoms.

Collagen supplement

Joint pain can be prevented by taking care of your body, and eating foods that promote healthy joints. Did you know that collagen is a protein that helps maintain cartilage? The more we take care of our bodies, the healthier it will be!

One of the keys to preventing joint pain is to protect the cushy cartilage that protects your bones. Cartilage is partially made up of a protein called collagen which plays a major role in the proper maintenance and strength of joint and ligament health. A 2014 review suggests that collagen can protect cartilage, relieve pain, and potentially increase bone strength.

Fish oil supplement (Omega-3 Fatty Acids)

One of the most popular supplements today is fish oil. This supplement may help you with inflammation that’s caused by arthritis, but more research needs to be done.

This is why fish oil has been studied extensively for its anti-inflammatory effects. One study found that people who had chronic pain from arthritis experienced less of it after taking 200mg of EPA and 400mg of DHA daily for 16 weeks.

Fish oil has also been proven to be an effective treatment for gout, a common but complex form of arthritis where symptoms tend to be more sudden and severe. Biting into a nice warm slice of apple pie with ice cream on the side is one of my favorite things in life.

Vitamin D supplement

Your bones are really important. You can’t move without them, and they’re the only thing that keeps you from collapsing in a pile of goop on the floor. That’s why it’s so important to get enough Vitamin D—especially since this nutrient not only helps your muscles contract, but also absorbs calcium and regulates phosphate.

Vitamin D is vital for strong bones—including the ones that make up your joints. According to the National Institutes of Health (NIH), Vitamin D helps you absorb calcium, one of the major building blocks of your bones. It also regulates phosphate, which allows you to contract the muscles that move the bones of your joints.

This is one of the most common reasons for pain in your bones, joints and muscles. Vitamin D deficiency is one of the leading causes for these pains. It’s important to have a healthy amount of vitamin D in your body to avoid this condition.

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