What is Red Yeast Rice extract?
Red yeast rice extract is a natural product made from indica rice that has been fermented with the red mold Monascus purpureus. It is popular in China, which has been used for centuries as food and medicine.
Red yeast rice extract is a popular ingredient in many Chinese dishes. For example, it is a food additive in Beijing roasted duck, ham, juice, etc. Red yeast rice extracts are also used in cosmetics and skin care products in conditioners for pregnant women. CIMA mainly provides functional red yeast rice extract.
Constituents of red yeast rice extract
More than 101 chemical constituents were isolated from red yeast rice, including monacolin, pigment, organic acid, sterol, naphthalene derivatives, flavonoids, polysaccharides, etc.
Functional red yeast rice products contain a substance called Monacolin K, and the natural monacolin K is greater than 0.4% red yeast rice. This is the most effective naturally occurring statin currently available. Like most statins, it lowers cholesterol levels in the blood by reducing the amount of cholesterol produced by the liver. Like most statins, it lowers cholesterol levels in the blood by reducing the amount of cholesterol produced by the liver.
Red Yeast Rice Forms and Specifications
CIMA offers red yeast rice powder and granules in specifications of 0.4%, 1%, 1.5%, 3%, 4%, 5%.
Monacolin k Introduction
Monacolin K exists in two forms: closed-loop lactone type (figure A) and open-loop acid type (figure B).
Lactone monacolin K was more stable than acid type. Monacolin K changes from acid to lactone in acidic environments. Monacline K of lactone type is less water-soluble than monacline K of acid type, and it is easy to crystallize or precipitate. Monacolin K degradation was induced by heating, and there was little difference between acid and lactone monacolin K degradation. Light intensifies the decomposition of Monaclin K. Acidic Monaclink is most similar in structure to HMG-COA reductase in the human body and forms a competitive mechanism with it to effectively inhibit cholesterol synthesis in the human body. Lactone monaclin K requires the binding of hydroxyesterase in the human body to inhibit cholesterol synthesis. There are differences between individuals and their ability to produce hydroxyl esterase is different, so acid monacline K is better than lactone monacline K in the human body.
Monacolin K VS Lovastatin
Monacolin K is not identical to lovastatin. Monaclink comes in two forms, lactone and acid. The lactone form of monacolin K and lovastatin are the same chemical. Lovastatin is the active ingredient in several medicines approved by the European Union to treat hypercholesterolemia.
Monacolin K and lovastatin are rapidly converted from their lactone to an identical hydroxy acid (HA) form, the latter being responsible for inhibiting the HMG-CoA reductase enzyme involved in cholesterol biosynthesis. While the acidic form naturally occurs in RYR, in the case of lovastatin, its generation requires conversion from the lactone form.
Red yeast rice with coq10
Red yeast rice naturally contains compounds similar to those found in statin drugs, commonly prescribed to treat high cholesterol. Statins can interfere with levels of Coenzyme Q10 (CoQ10), a nutrient vital for heart and muscle health. Low levels might also exacerbate specific symptoms associated with these treatments. Because of their similarity, some concern exists that red yeast rice could also alter CoQ10 levels, based on the University of Maryland Medical Center.
Red Yeast Rice Manufacturing Process
Sterilization, seed culture medium, red yeast rice fermentation, drying are the key quality control points:
- Sterilization: sterilization at 121 degrees for 20 minutes
- Seed culture medium: pure seed culture is required, and the temperature is 30 degrees, and the culture time is 48 hours.
- Fermentation of red yeast rice: temperature 30 degrees, humidity 60-90%, to prevent contamination of miscellaneous bacteria in the fermentation process.
- Drying: time is 12-14 hours, and the temperature is 110 degrees.
Safety of CIMA’s Red Yeast Rice Extracts
- High proportion of acid form Monacolin k, which has fewer side effects than lactone form. Acid form VS lactone form is 80:20,
- Citrinin free
- Irradiation Free
- 100% Solid Fermentation, which ensures less bacterial contamination.
Where to buy red yeast rice extract powder in bulk?
If you are trying Red Yeast Rice Extract in your supplement formula and want to know the Red Yeast Rice Extract pricing and where to buy Red Yeast Rice Extract in bulk quantities, you come to the right place.
Wuxi Cima Science Co., Ltd. is a professional producer of Red Yeast Rice Extract, such as powder and granules. Commercial production and ready stock are available.
CIMA offers red yeast rice powder and granules in specifications of 0.4%, 1%, 1.5%, 3% 4% 5%.
Your inquiry regarding price, COA, MOA, MSDS, flow chart, etc., will be answered within 12 hours.
– Are you a manufacturer, trading company, or a third party?
We’re a manufacturer with a history of 16 years.
– Is your red yeast rice extracts the same as the ingredients in lovastatin?
No, lovastatin is lactone from Monacolin k, which has many side effects. Functional red yeast rice extracts contain 80% acid from Monacolin K and 20% lactone from Monacolin K, which ensures fewer side effects for the human body.
– Can you provide contract manufacturing and private label service?
Yes, we can provide contract manufacturing and private label service per your request.
– Is your functional red yeast rice mostly used for drugs?
No, our customers mostly use it as a dietary supplement for human body health.