What is diosmetin?
Diosmetin powder, CAS 520-34-3, is the aglycone of the flavonoid glycoside diosmin, which occurs naturally in citrus fruits. In citrus, there are already many active ingredients commercially available as bulk raw powders, such as hesperidin, diosmin, hesperitin, synephrine, neohesperidin, naringin, methyl hesperidin, methyl hesperidin chalcone, naringin dihydrochalcone, and citrus bioflavonoid, etc. However, diosmetin may be the least popular one among them. All these flavones are generally regarded as safe (GRAS) and used in dietary supplement formulas, but diosmetin is too new to get noticed.
Natural sources of diosmetin
Diosmetin has been identified in the following plants:
Capsella bursa-pastoris (Shepherd’s Purse plant),
- Citrus limon (lemon),
- Mentha spicata (spearmint plant),
- Origanum vulgare (oregano),
- Rosmarinus officinalis (rosemary plant),
- Salvia officinalis (sage),
- Salvia tomentosa (sage),
- Tanacetum vulgare (tansy plant),
- Thymus vulgaris (thyme plant).
Diosmetin is found naturally in citrus fruits and juices, such as orange juice, grapes and grapefruit. According to Wikipedia, diosmetin can be also found in caucasian vetch,legume Acacia farnesiana Wild and Olea europaea L. leaves.
Manufacturing process of diosmetin
If you search diosmetin powder on the internet, all the information of diosmetin is from China, and all the botanical sources are from Lemon peel extract (Citrus limon). Anyway, this is not the truth.
The production process of standardized diosmetin extracted from lemon Citrus Iimon (L) Burm peel has many limitations:
- The yield from lemon peel extract is very small while its cost is very high, and it is not possible to manufacture 10 tons or more at a time.
- The price for bulk diosmetin 98% powder from lemon peel is over USD 500/kg. It’s too expensive compared with other similar ingredients.
Wuxi Cima Science Co., Ltd develops a new method for commercially extracting diosmetin from Citrus aurantium L, of course, not from lemon peels, resulting in bulk quantities (10 tons per month) and much lower prices. If you are interested in knowing the manufacturing process and bulk pricing, please write to us by email from the contact page or just click the send inquiry button.
Where to buy bulk diosmetin powder 98%?
Wuxi Cima Science Co., Ltd is a professional manufacturer of diosmetin 98% powder in large quantities. 10 tons of diosmetin ingredient is in inventory. Our package is 25kg/drum, and free sample such as 5g to 10g can be obtained upon your request through email inquiry.
