Nicotinamide Riboside Granular Powder Manufacturer

Nicotinamide Riboside Chloride Granules Manufacturer in China

Nicotinamide Riboside Granular Powder

Product name	Nicotinamide Riboside Chloride Granular Powder
Synonyms	Nicotinamide Riboside Granules, NR Granular Powder, NR Granules, Nicotinamide Riboside Coarse Powder,Pyridine-3-carboxamide riboside chloride, Niagen equivalent raw material, NR Chloride Granular Crystals, 20–60 Mesh NR Granules
CAS Number	23111-00-4
Molecular formula	C₁₁H₁₅N₂O₅.Cl
Molecular weight	290.70 g/mol
Specifications	97%min
Appearance/Color	White to off-white granules
Solubility in water	446.5mg/ml
Melting point	115℃-125℃
Benefits	Boosts NAD+ levels, Supports longevity, healthy Aging
Applications	Dietary supplement, functional foods, and beverages, Energy supplements,
Package	1kg/bag,25kg/drum

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Description

What is Nicotinamide Riboside?

Nicotinamide Riboside (NR) is a naturally occurring form of vitamin B3 and a key precursor of nicotinamide adenine dinucleotide (NAD⁺), a coenzyme involved in cellular energy metabolism and mitochondrial function. Small amounts of NR are found in foods like milk and yeast, but commercial NR for supplements is produced through controlled synthesis for high purity. The main form used in supplements is Nicotinamide Riboside Chloride (NR chloride) with CAS No. 23111-00-4, molecular formula C11H15N2O5Cl, and molecular weight 290.70 g/mol. High-quality NR has a purity of at least 99% (HPLC) and appears as a white to off-white powder or granular powder. It is highly soluble in water, allowing efficient formulation in dietary supplements. NR is valued for its bioavailability, as it is efficiently converted into NAD⁺ through the body’s NAD⁺ salvage pathway. Commercial products are supplied in 25 kg fiber drums with double PE bags for bulk distribution. Cima Science is a leading bulk Nicotinamide Riboside powder supplier in China, providing high-purity NR chloride for nutraceutical manufacturers worldwide. We also offer OEM supplement services, including capsules, tablets, powders, and customized formulations.

In the dietary supplement market, several Nicotinamide Riboside derivatives have been developed to improve stability or formulation compatibility, including Nicotinamide Riboside Chloride, Nicotinamide Riboside Malate, and Nicotinamide Riboside Hydrogen Malate. Among these derivatives, Nicotinamide Riboside Chloride (NR chloride) remains the most widely used and commercially available form. This salt form offers excellent chemical stability, high purity, good water solubility, and reliable bioavailability, making it well-suited for large-scale nutraceutical manufacturing. Because of these advantages, NR chloride is the dominant form used in NAD⁺ booster supplements and is commonly supplied as a powder or granular powder for capsule filling, tablet compression, and dietary supplement blends.

Nicotinamide Riboside Granules vs NR Powder

Nicotinamide Riboside Chloride is commercially supplied in two forms: fine powder (80-200 mesh) and granular powder (20–60 mesh). Both contain the same active ingredient, but the granular form offers several advantages for supplement manufacturing.

Form	Particle Size	Manufacturing Characteristics
Nicotinamide Riboside Powder	Fine powder (usually 80–200 mesh)	Faster dissolution but more dust and lower bulk density
Nicotinamide Riboside Granules	20–60 mesh	Better flowability, improved stability, easier capsule filling

Advantages of Nicotinamide Riboside Granules

Improved Thermal Stability

One of the most important advantages of NR chloride granules is enhanced thermal stability. The granulation process helps protect the active ingredient and improves stability during tablet compression, capsule filling, and other manufacturing processes that may involve heat.

Higher Bulk Density

Granules typically have higher bulk density than fine powders. This allows manufacturers to:

Improve capsule filling efficiency.
Achieve more uniform tablet compression.
Reduce material loss during processing.

Higher density also helps maintain consistent dosage in supplement formulations.

Better Flowability for Production

Fine powders can have poor flow properties, which may cause problems during automated production.

NR granules provide:

Smooth flow through production equipment
More consistent blending
Reduced clogging during capsule filling

These properties make granular NR particularly suitable for large-scale supplement manufacturing.

Reduced Moisture Absorption

Granules generally have a lower surface area compared with fine powders, which helps reduce moisture absorption during storage and handling.

This contributes to:

Improved product stability
Reduced risk of clumping or caking
Better shelf stability

Reduced Dust During Processing

Fine powders may produce dust during mixing and handling, leading to material loss and equipment contamination. Granular powder reduces dust formation, improving the working environment and production efficiency.

NR granules are ideal for Capsule and Tablet Manufacturing. Due to these advantages, Nicotinamide Riboside Granular Powder (20–60 mesh) is widely preferred for:

Capsule filling
Tablet compression
Powder blends
Large-scale supplement production

Improved flowability, density, and stability make NR granules a practical choice for modern nutraceutical manufacturing lines.

Nicotinamide Riboside Granules vs NR Powder

Where to buy bulk NR granules?

For a dependable source of bulk Nicotinamide Riboside granules or granular powder (NR chloride), partnering directly with a manufacturer provides stable quality, consistent supply, and competitive pricing. Our Nicotinamide Riboside Chloride granular powder, typically available in 20–60 mesh, offers excellent flowability and density, making it well-suited for capsule filling, tablet compression, and supplement powder blends.

Cima Science is a leading manufacturer of longevity ingredients, specializing in Nicotinamide Riboside (NR), NMN(Nano Liposome NMN Powder), and NAD⁺ precursors for the global nutraceutical industry. We supply high-purity Nicotinamide Riboside Chloride granules and granular powder to supplement brands, contract manufacturers, and distributors worldwide. All products are produced under strict quality standards and are Halal, Kosher, and ISO certified.

Beyond standard 20–60 mesh NR chloride granules, Cima Science can customize mesh sizes to meet specific manufacturing needs. We offer competitive wholesale pricing, free evaluation samples, and bulk packaging in 25 kg drums. Our OEM services include capsules, tablets, and custom formulations. Contact us to request a quote or to source high-quality Nicotinamide Riboside granular powder directly from the manufacturer.

Your inquiry regarding price, COA, MSDS, MOA, flow chart, etc., will be answered in 12 hours.