What is Nicotinamide Mononucleotide?
Nicotinamide mononucleotide, abbreviated as NMN, has the following names:
β-NMN, BETA-Nicotinamide Mononucleotide;
BETA-NMN; BETA-NICOTINAMIDE MONONUCLEOTIDE;
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;
NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-PHOSPHATE; NICOTINAMIDE RIBOTIDE;
NMN exists in various organisms, including humans, and is a compound essential for maintaining bodily functions. NMN is reused after being metabolized by the body, and vitamin B3 in food can also synthesize NMN.
Nicotinamide mononucleotide (NMN) is an essential precursor of NAD+, and NAD+ is a crucial means of cell repair in humans. When humans are infants and young children, their growth and development are extremely rapid, and with the increase of age, the human body function will gradually decline. In the aging process of human cells, the amount of NAD+ will be much reduced compared with the past due to metabolism and the body itself.
Some formulas are with only NNN in them, and some are together with other active ingredients, such as bulk resveratrol, pterostilbene, showed root extract, etc.
Nicotinamide Mononucleotide VS. Nicotinamide Riboside
Nowadays, the world is rich in various research with NR, and the experiment of the human body makes the result of NR on theoretical data better than NMN. However, studies have shown that NR powder begins to function in the human body and still needs to be experienced for a while. The key is that NR and NMN are precursors of NAD+, while Nicotinamide Riboside (NR) is a precursor of NMN and NAD+, so NR is changing. It takes a while before NAD+. Compared with the immediate effect of NMN, the 15 minutes of NR is a big gap.
It can be seen from the above cycle diagram that NAMPT is a crucial factor limiting the generation of NMN. As age increases, not the human body does not want to be younger, but the enzyme activity of NAMPT decreases when energy and nutrients are supplied. As the cycle of NAM is reduced, the stock of NAD+ is naturally reduced.
NR can be converted to NMN or to NAM, depending on the role of the Nrk1 enzyme to determine which substance of the same quality NR will produce more. If it is converted to NAM, it is also restricted by NAMPT enzyme. Compared with the direct action of NMN to generate NAD+, the effect of an equal amount of NR is obviously weakened a lot.
Why not take NAD+ powder?
NAD+ cannot be directly taken up into the cells by oral administration because of its excessive molecular weight. The supplement of NAD+ is only achieved by ingesting a small molecular weight NAD+ precursor.
However, NMN can be made into a variety of products, which can be capsules, tablets, or even granules due to its soluble nature. The solubility of NMN in water is 35mg/ml.
In this sense, NMN is much better than NAD+, and more direct than nicotinamide riboside.
Where to buy NMN bulk powder?
If you are trying Nicotinamide Mononucleotide powder in your supplement formula and want to know the pricing of Nicotinamide Mononucleotide and where to buy NMN powder in large quantities, you come to the right place.
Wuxi Cima Science Co., Ltd. is a professional manufacturer of bulk nutritional raw ingredients.
Our Nicotinamide Mononucleotide is in raw powder form, 99% min.
Your inquiry regarding price, COA, MSDS, MOA, flow chart, etc., will be answered in 12 hours.