What is S-Adenosyl-L-Methionine?
S-Adenosyl-L-methionine is simply called SAMe or SAM-e in America, and also aliased as AdoMet or SAM. The names S-adenosyl methionine and S-adenosylmethionine also mean same substance S-Adenosyl-L-methionine. It is present naturally in the human body and plays an essential role in kinds of reactions in the body.
SAMe donates methyl group in kinds of biosynthesis of proteins, neurotransmitters, nucleic and nucleic acids. This happens in many enzymatic transmethylation reactions.
Why do manufacturers make S-adenosyl-L-methionine disulfate tosylate instead?
People have known the biological importance of S-Adenosyl-L-methionine for many years, but it has been only developed recently. Why? Because S-Adenosyl-L-methionine is extremely unstable for moisture and temperature. When the temperature is above 0 °C or the SAMe discloses in a high humidity environment, the assay will degrade soon. Then the SAMe lost its biological activity because the S/S form((SS)-(+)-S-adenosyl-L-methionine) converted into R/S((RS)-(+)-S-adenosyl-L-methionine) form. It is a problem for the preparation of formulations.
Researchers also proved that the trehalose could protect SAMe from degradation.
What other names does S-adenosyl-L-methionine disulfate tosylate have?
adenosyl-L-methionine disulfate p-toluenesulfonate
Adenosyl-L-methionine Disulfate Tosylate
S-adenosylmethionine tosylate disulfate
SAM tosylate disulfate
Ademetionine disulfate tosylate
What are the characteristics of S-adenosyl-L-methionine disulfate tosylate?
S-adenosyl-L-methionine disulfate tosylate is the disulfate form of the p-toluene-sulfonate complex of SAMe. It converts into active SAMe in cells to play its role. The structure of S-adenosyl-L-methionine disulfate tosylate is as follows:
Where to buy s adenosyl l methionine?
CIMA Science always supplies high-quality S-adenosyl-L-methionine disulfate tosylate to the market; the bulk stock is available in both Chinese and Los Angeles warehouses.
