What is Pterostilbene?
Pterostilbene powder (trans-3,5-dimethoxy-4-hydroxystilbene) is a naturally occurring polyphenol molecule in plants. Pterostilbene was named after the Pterocarpus family plants, the first sources of pterostilbene to be found. Originally, the compound was isolated from the red sandalwood tree (Pterocarpus santalinus) and later from Pterocarpus marsupium. Pterocarpus plants have several names worldwide, including Paduak, Malabar kino Vijayasar, Narra, and Indian kino tree.
Trans-pterostilbene
Some supplements are labeled “trans-pterostilbene,” not just “pterostilbene.” This compound has many names, one of which is trans-3,5-dimethoxy-4′-hydroxystilbene.
In chemistry, the word “trans” means certain atoms (or groups of atoms) are on opposite sides of a molecular physical structure. The term “cis” means that those atoms are on the same side of the molecule. Both trans- and cis-pterostilbene are found in nature, while the trans form is more stable.
Pterostilbene, without a modifier, generally default refers to the trans form. The cis-type is always called cis-pterostilbene.
Food sources of Pterostilbene
Pterostilbene is a polyphenol naturally found in nuts, vegetables, and fruits, particularly blueberries.
- Pterostilbene is detected in berries of the Vaccinium genus, a group of shrubs including many types of berries, of which blueberries and cranberries are the most widely available. Blueberries are the most abundant dietary source of pterostilbene. The estimated content per blueberry varied between 99 ng to 520ng, depending on the type of blueberry.
- Other berries include cranberry, bilberry, lingonberry or cowberry, and huckleberry.
- Red grapes, both the berries and leaves. Pterostilbene is also thought to contain small amounts in red wine (just like resveratrol).
- Heartwood, also called Indian Kino Tree (Pterocarpus marsupium).
- Sandalwood (pterocarpus santalinus), is also the source of rosewood and is known in China as Zita.
Pterostilbene VS Resveratrol
Pterostilbene and Resveratrol are a class of compounds called phytoalexins in plants, which defend against microbes and parasites. Both of them have antioxidant, anti-inflammatory, and anticarcinogenic properties.
On the chemical level, pterostilbene and resveratrol are very similar. However, the two behave differently in body absorption. Pterostilbene stays longer in the body because it contains only one hydroxyl group. It can cross the membranes easier than resveratrol and stay longer in the body. Resveratrol has a half-life of 14 min because it contains three hydroxyl groups, making it easier for the body to eliminate the molecule.
Pterostilbene has higher bioavailability than resveratrol and other stilbenes due to two methoxy groups, which allow it to exhibit increased lipophilicity and oral absorption. In animal studies, pterostilbene was shown to have 80% bioavailability versus 20% for resveratrol.
Where to buy bulk pterostilbene powder
Wuxi Cima Science Co., Ltd is a nutritional raw material manufacturer with 3 plants and one R&D center. Cima is committed to quality, purity, and integrity.
Pterostilbene 99% powder is our main product in large quantities. Our package is 25kg/drum. Please email us if you want to know the price and technical documents, such as COA and MSDS; A free sample is available.
Pterostilbene Powder Specification and Price
Pterostilbene powder 99% is one of our main products. It is a relatively mature market product with slight price fluctuation. The price range is about USD 310 – USD 380 in China market. We will offer you the most favorable price with high quality. A free sample is available upon your request.
Mfg flow Chart of Trans-Pterostilbene
Cima Science is a professional manufacturer of Pterostilbene powder, and here is the manufacturing flow chart:
3,5-dimethoxybenzaldehyde and para-hydroxyphenyl methanol were used as ingredients.
According to the Wittig-Horner method, the 3,5-dialkyl phosphonate reagent was used under an alkaline catalyst and reacted with the reflux temperature at room temperature. Finally obtains diphenylethylene compounds.
Adopting diphenylethylene compounds to prepare the method for Pterostilbene, in the solvent of methanol or ethanol, with an acid catalyst, to the de-pyrans protecting group of diphenylethylene compounds, obtain distyrene;
