What is Stearoyl Vanillylamide?
Stearoyl vanillylamide is one of the most famous capsaicin analogs and is a naturally occurring capsaicin analog found in red pepper species. Capsaicin is the cause of the heat/burning sensation caused by pepper. Unlike other types of capsaicin in the same category, Stearoyl vanillylamide is unique in that it is non-steroidal, meaning it does not produce the “spicy” or irritating effects of capsaicin.
Generally, like other capsaicin analogs, this compound acts by enhancing the release of epinephrine and norepinephrine. These hormones are required to activate various sympathetic body reactions such as metabolism. Therefore, stearoyl vanillylamide ultimately contributes to the burning of brown fat in adipose tissue or subcutaneous tissue.
What are the benefits to use Stearoyl Vanillylamide? The inclusion of stearic acid amide has several advantages in the preparation of health supplements. As many studies are still ongoing, scientists are looking forward to discovering more of the benefits of using this compound. The following are some of the advantages which are known for using Stearoyl vanillylamide:
It effectively breaks down belly fat
Stearoyl vanillylamide acts as non-irritating capsaicin that can stimulate brown adipose tissue or brown fat (fat is mainly found in the mitochondria and produces heat in the body). Fat is found in all parts of the body, including the arms, thighs, abdomen and gluteal muscles. Although most people can quickly get rid of fat in other areas, burning belly fat is considered a real burden. Studies have shown that taking Stearoyl vanillylamide can help break down fats that are particularly located in the abdomen. This is achieved by activating TRPV1, an enzyme that prevents abdominal fat production and fat formation. Together with capsaicin, Stearoyl vanillylamide is considered to be one of the agents that target and activate TRPV1 (transient receptor potential vanilloid) located in the plasma membrane (except for endogenous ligands, inflammatory mediators and non-selective stimuli). Responsible for encoding an integral membrane protein as an ion channel. When TRPV1 is specifically activated on sensory fibers and non-neuronal cells, it will result in the influx of calcium and sodium, which is necessary for membrane depolarization (polarity transition; from negative to positive, leading to positive Positive effects) Cell function and its communication.
Stearoyl vanillylamide and capsaicin, they have similar structures and characteristics, but in some respects, Stearoyl vanillylamide is more advantageous.
Stearoyl vanillylamide (SVA) VS Capsaicin：
| SVA | Capsaicin | |
| Mechanism | 1, activate the sympathetic body reaction, improve metabolism, promote fat burning, healthy weight loss. 2. This ingredient can be mixed with other ingredients for fat burning and energy enhancers. | 1, resisting the secretion of gastric acid, weakening the gastric motility, thereby decreasing the digestive capacity of the stomach, increasing the time of satiety, thereby reducing appetite.
2. Promote productivity and heat production in the body. Activates brown adipose tissue, promotes oxidation of fatty acids, and promotes energy metabolism.
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The difference |
Has a similar function of capsaicin, but no spicy taste does not irritate the stomach, high safety, no side effects. | A large amount of capsaicin has a strong stimulating and harmful impact on the gastric mucosa, and its toxic side effects limit its clinical application. |
It acts as an anti-inflammatory agent
Although not fully confirmed, some studies have shown that Stearoyl vanillylamide may effectively reduce inflammation by activating TRPV1 and releasing adrenergic hormones. An increase in the levels of adrenaline and norepinephrine in the body easily promotes the function of the immune system, thereby healing and controlling inflammation more quickly. Also, when TRPV1 is activated, it can be considered as a therapeutic agent for inflammation. Further research indicates that capsaicin alleviates neurogenic inflammation, which makes it accessible recently.
It enhances the energy level
According to an experiment conducted in Japan, stearoyl vanillylamide improves swimming ability whether or not it is irritating. The study was performed orally on mice, using an adjustable current pool, which showed that Stearoyl vanillylamide promotes adrenaline secretion (adrenalin-estrogen secreted by the adrenal gland; especially when stressed, angry or stressed) Release in the blood leads to increased heart rate, increased muscle strength and blood pressure, which results in better energy in rats compared to other mice not given Stearoyl vanillylamide. Also, studies have shown that non-irritating CAP analogs promote adrenaline secretion. Thus, stearoyl vanillylamide is the candidate. With the effects of adrenergic hormone activation, scientists believe that stearoyl vanillylamide can help increase energy levels after lipolysis. At a sufficient energy level, individual users can perform efficiently in all areas, such as the workplace and school, without feeling tired.
It may lower blood pressure
This study shows that the action of stearoyl vanillylamide is only carried out in mouse subjects and has not been carried out in humans. Experts believe that the compound may help lower blood pressure by causing peripheral vasodilation. However, this benefit remains to be further studied. Conclusion:
Some animal studies and experiments have shown its usefulness in humans, but there is still not enough evidence to prove that it and human trials are still in progress, but humans can better tolerate this because it has less compared to capsaicin. Irritating and cannot be taken because it is more annoying.
Stearoyl vanillylamide is a new product on the market, especially in supplements, which few diet companies use as ingredients. Instead, this ingredient is typically mixed with other ingredients specifically for fat burning and energy enhancers. It is usually safe to use stearoyl vanillylamide as long as a healthy person takes it within the dosage range recommended by the doctor.
Where to buy Stearoyl Vanillylamide?
Wuxi Cima Science Co., Ltd is the manufacturer of stearoyl vanillylamide.
Cima can offer the specification of Stearoyl Vanillylamide 98%. If you need to know more about Stearoyl vanillylamide like COA, MSDS, and price, please email us, and we will get back in 12 hours.
Packing Detail: Packed in paper drums and two plastic bags inside.
Net Weight: 25kg/drum.
Storage Situation: Stored in a well-closed container away from moisture and direct sunlight.
Shelf Life: Two years if sealed and stored properly.
