What is Ginkgo Biloba?
Ginkgo Biloba, usually called Ginkgo or Gingko, is known as one of the oldest species of tree in the world and has been native to China with more than 2800 years of history. Each part of ginkgo biloba has its nutrition value.
Ginkgo nuts (the fruit of Ginkgo tree) is useful as a source of food. Ginkgo seeds contain substances that might kill the bacteria and fungi that cause infections in the body. Ginkgo leaf extract has been used widely for traditional medicines and dietary supplements.
Uses of Ginkgo
As one of the pervasive herbal medicines, more and more people like to intake Ginkgo biloba extract as a regular diet nutrition supplement. It is extracted from the dried green leaves and processed into some different forms: liquid extract, capsules, soft gels, and tablets.
Phytochemicals in Ginkgo Biloba Extract
Gingko leaf is rich in flavonoids and terpenoids which are associated with antioxidants. The flavonoid fraction accounts for 24% of the extract and terpenes (ginkgolides and bilobalide) for 6%. It also contains high levels of quercetin glycoside, kaempferol glycoside, the bitter ginkgolides A, B, C, J and M, and bilobalide. Phenols, tannins, bilobol also exist in the leaves.
All these substances protect against oxidative cell damage from harmful free radicals.
Cima Science Ginkgo leaf extract active ingredient analysis
|Test Items||Specification||Test Results|
|HPLC||K/Q NLT 0.7||1.0|
|HPLC||I/Q NLT 0.1||0.37|
Total flavone glycosides, %
(Calculated as flavonol glycosides, on the dried basis）
Quercetin glycosides/ kaempferol glycosides ratio
|Quercetin glycosides content ＜55% of total glycosides cotent||
Terpene lactones, %
|Ginkgolic acids, ppm||NMT 5.0||0.7|
How does ginkgo biloba work?
Ginkgo can lower blood platelet activity factor (PAF), similar to the effect of aspirin on blood thinning. Excessive PAF is associated with cardiovascular disease, brain damage, hearing impairment, and other immune and inflammatory diseases.
Ginkgo biloba leaves increase the production of adenosine triphosphate (ATP), a significant source of energy at the cellular level. ATP has been shown to enhance the brain’s ability to convert glucose into energy and increase electrical activity.
Ginkgo flavonoids can soften tiny capillaries and have a positive effect on various organs of the body, especially the brain.
Ginkgo Biloba Benefits
Because of its potential antioxidant properties, ginkgo biloba has benefits for the brain, retina, and cardiovascular system. It can reduce the damage of free radicals and reduce the extent to which brain function declines with age, naturally delaying the aging process.
It may also promote metabolism, regulate neurotransmitters, and promote oxygen delivery to the brain.
Extract of Ginkgo biloba can improve mental clarity and memory retention. One clinical study found that the extract of ginkgo biloba was effective in treating Alzheimer’s dementia.
Improves Blood Circulation
Ginkgo biloba can enhance the absorption of oxygen and purify the blood. It also prevents blood from thickening and reduces the chance of thrombosis.
An investigation test found that people with a generalized anxiety disorder can control the production of stress hormones adrenaline and cortisol with intaking ginkgo extract.
Reduces PMS Symptoms
Several types of research indicated that EGb 761 could effectively fight symptoms of Pre-menstrual Syndrome (PMS), such as anxiety, mood swings and fatigue.
Protects the Eyes
Ginkgo Biloba is an effective tonic for improving the blood flow in the eyes and protects the eyes from pollutants.
Good for skins
As we introduced in the beginning, ginkgo leaf is rich in antioxidants. It can relieve the stress of the derma due to age go, then fight wrinkles and fine lines.
Ginkgo Extract Complex with Other Nootropic Supplements
Ginkgo biloba goes well with some other nootropic ingredients to double enhance intelligence growth.
Ginkgo biloba with vinpocetine is an approved complexation by FDA.
Gingko Biloba &Panax ginseng has been a traditional herbal combination for many years.
Many preclinical studies support the efficacy of the complexation of Ginkgo extract and Phosphatidylserine
Ginkgo biloba with Coenzyme Q10 is a top-selling supplement for cognition.
Ginkgo extract can also combine with Magnesium L threonate, Alpha GPC, Bacopa Monnieri, and DAME, etc. to promote memory and concentration.
Ginkgo biloba Dietary Dosage
Clinical trials said the extracts of ginkgo mostly are standardized to 24% flavone glycosides and 6% terpene lactones.
For Alzheimer’s Disease，40-120mg, three times a day.
For cognitive enhancement, 120-240mg, 1-4 hours before the performance.
Are there any possible adverse effects of ginkgo extract?
There are few potentially harmful substances like ginkgo toxin (4-O-Methoxypyridoxine) in the ginkgo leaves. It usually can’t affect any due to too little content if we intake ginkgo biloba capsules, tablets or soft gels following the recommended dosage. Nevertheless, it will result in headache if intake too much ginkgo biloba supplement, due to the compound 4-O-Methylpyridoxine which interferes with the synthesis of GABA, a neurotransmitter in the brain.
Some other side effects reaction as Allergic skin reactions, Dizziness and Constipation
What’s the advantage of Ginkgo Biloba extract (GBE) at Cima Science Co., Ltd?
We can supply good stable quality Ginkgo leaf extract with the standard of Cph, USP, and EP.