What’s Oleoylethanolamide (OEA)?
Well, oleoylethanolamide is something new to the nutritional market as a popular dietary supplement ingredient used in weight loss formulas. Many bodybuilding fans are discussing oleoylethanolamide on Reddit and other social networking platforms.
Oleoylethanolamide consists of three words: oleoyl ethanol amide (so you can pronounce and memorize it more easily). However, Oleoylethanolamide is still too long for users to memorize it, and experts use OEA to refer to it. (The first letter of the three words)
Oleoylethanolamide is a natural metabolite of oleic acid made in the small intestine within the human body. It is naturally occurring, and experts call it “endogenous.”
Oleylethanolamide VS cannabinoid anandamide
The effects of OEA were first studied because it shares similarities with another chemical, a cannabinoid known as anandamide. Cannabinoids are related to the plant Cannabis, and anandamides present in the plant (and marijuana) can increase a person’s desire to snack by triggering a feeding response. According to Wikipedia, Oleoylethanolamide is the monounsaturated analogue of the endocannabinoid anandamide. Although OEA has a chemical structure that is similar to anandamide, its effects on eating and weight management are different. Unlike anandamide, OEA acts independently of the cannabinoid pathway, regulating PPAR-α activity to stimulate lipolysis.
Structures of various fatty-acid ethanolamides: oleoylethanolamide (OEA), palmitoylethanolamide (PEA) and anandamide (arachidonoylethanolamide, AEA). (Cima Science Co., Ltd is the only manufacturer of bulk raw materials of OEA, PEA and AEA in China, if you need sample and price quote, please drop us an email in the contact us page.)
OEA binds with high affinity to the peroxisome-proliferator-activated receptor-a (PPAR-a), a nuclear receptor that regulates several aspects of lipid metabolism.
Natural sources of oleoylethanolamide
Oleoylethanolamide is a natural metabolite of oleic acid. Therefore, foods containg oleic acid is a direct source of OEA.
Oleic acid is the primary fat in vegetable oils such as olive, canola and sunflower. Oleic acid can also be found in nut oils, meat, poultry, cheese, etc.
Dietary sources rich in oleic acid include:
High Oleic Safflower Oil
Some popular fat sources for high oleic acid in the table:
|Rice bran oil
Some facts about Oleic Acid:
- One of the most common fats in human breast milk
- Makes up 25% of fat in cow’s milk
- Omega-9 fatty acid
- Chemical formula is C18H34O2(CAS 112-80-1)
- Hangs out with triglycerides
- It is used in high-priced cosmetics as a very effective moisturizer
- Found in milk fat, cheese, olive oil, grapeseed oil, nuts, avocados, eggs and meat
- It may be responsible for most of the health benefits of olive oil.
The manufacturing process of Oleoylethanolamide
Cima Science Co., Ltd may be the only OEA manufacturer in China with mass production. The flow chart of Oleoylethanolamide is below:
General steps is: reactiong→Purification process→ Filtration→Re-Dissolved in ethanol→hydrogenation →Filtrate Clear Liquid→crystallization→Filtration →Testing→ Packing → End Product
If you have questions regarding the technical process, please feel free to contact us.
Where to buy Oleoylethanolamide powder in bulk?
Cima Science Co., Ltd is the largest manufacturer of bulk oleoylethanolamide in China. Make sure that our OEA is raw materail in powder form instead of capsules or tablets. Some companies use oleoylethanolamide powder (standardized to 15% oleoylethanolamide) or oleoylethanolamide oleic acid 50% in their finished products. The specifications of Cima OEA is 90% min, up to 95%, qulity is satisfied among our buyers in the United States and Europe.
At present, 20 tons of oleoylethanolamide 90% powder is ready in stock. If you want to know OEA pricing and technical documents such as certificate of analysis, MSDS, please kindly send us an email.
What’s the advantage of Cima’s OEA Oleoylethanolamide?
Cima is the First and unique manufacturer of OEA (Oleoylethanolamide) in China, with regular stock available.
What’s the MOQ for Cima OEA?
We don’t set MOQ for OEA. It’s okay for you to order any amount from 1kg to 1000kg.