What is Maslinic acid?
Maslinic acid is a versatile natural ingredient known as triterpene. It is used as dietary supplements for bodybuilding, skin care in cosmetics, and anti-cancer agent in medicines.
Natural sources of Maslinic Acid
There are different specifications and natural sources for maslinic acid.
Generally speaking, there are three main sources:
- Olive (Olea europaea) High concentration of maslinic acid is found in the waxy skin of olives, reaching as high as 80%.
- Crataegus pinnatifida (aka Chinese hawthorn, or Hawthorn berry)
- Eriobotrya japonica (Thunb.) Lindl (loquat leaves)
Eriobotrya japonica is unique to China, and you’ll find all suppliers who supply maslinic acid from loquats are from China.
According to Wikipedia, Maslinic acid is a byproduct of olive oil extraction from dry olive-pomace oil. It seems that olive is the main source of mass production of maslinic acid powder. However, it is probably not. It’s difficult to isolate maslinic acid from olive leaves or oils. And the cost is also quite high.
In reality, the loquat leaf extract is the best source.
Loquat source is new to the market; Loquat is abundant; the production technology is easy to operate.
Maslinic acid specifications
Maslinic acid 10% is the most popular specification.
Of course, 20%, 30%, 50%, 70%, 98% are all available upon your reuqest.
Cima is able to offer maslinic acid powder from both loquat leaf extract and olive (Olea europaea), but the pricing is quite different.
Chemical constituents of loquat leaf extract
As the origin of loquat plants, China has cultivated loquat for more than 2000 years. Loquat is now commercially cultivated in more than 30 countries worldwide.
China is now the largest producer of loquat fruit with a cultivation area of about 170,000 ha and an output of about one million tons per year, accounting for more than 70% of the world’s total loquat production.
Loquat leaf extract has been listed in Chinese Pharmacopedia mainly used to clear the lung and relieve cough, reduce adverse reactions and stop vomiting. It is used for coughing with lung heat, asthma, stomach heat, and vomiting, hot and thirsty. Loquat leaves are also listed in the Japanese Pharmacopeia and are used widely as a traditional herbal medicine for the treatment of chronic bronchitis and coughs.
The pharmacodynamics of loquat leaves are mainly concentrated in the anti-inflammatory, hypoglycemic and antiviral activities of triterpenoids.
The main active triterpenes in Eriobotrya japonica are oleanolic acid, ursolic acid, corosolic acid, and maslinic acid.
Based on another statistics of loquat leaves from 10 regions in China,
the content of maslinic acid ranged from 0.244% to 0.571%.
The content of corosolic acid ranged from 0.352% to 0.808%.
The content of oleanolic acid ranged from 0.146% to 0.192%.
The content of ursolic acid ranged from 0.548% to 0.834%.
Benefits of Maslinic acid
As mention before, maslinic acid can be beneficial to bodybuilding, skin care, and anti-cancer potentials.
Maslinic acid for bodybuilding
Maslinic Acid is a new ingredient for muscle growth.
Animal studies have shown that maslinic acid has a powerful anabolic effect by increasing whole body growth rate, increasing liver protein synthesis and nitrogen retention.
In animal studies, scientists studied the effects of maslinic acid on growth, protein-turnover rates and nucleic acid concentration in trout white muscle. The trout is a kind of fish.
Five groups of 180 trout of a mean body mass of 20 grams were fed for 225 days with diets containing 0, 1, 5, 25 and 250mg of maslinic acid per kg of diet. At the end of the experiment, white-muscle weight (which is their fast-twitch muscle) and protein-accumulation rate of trout fed with maslinic acid were higher than in the control group. The total content of DNA, RNA, and protein in trout fed with 25 and 250mg of maslinic acid per kg body weight was significantly higher than in the control. The protein: DNA ratio was also slightly higher than control.
In the same groups of trout, protein synthesis rates increased to more than 80 percent over the control values, while no differences were found in protein-degradation rate. Thus, maslinic acid can act as a growth factor when added to a standard trout diet.
You may find the full documents entitled Maslinic acid added to the diet increases growth and protein-turnover rates in the white muscle of rainbow trout (Oncorhynchus mykiss) here. It’s very encouraging.
Supplements containing Maslinic acid
At present, Maslinic acid 10% and Maslinic acid 70% are the two main specifications in the current supplement formulas.
Olive pomace oil (standardized for 70% Maslinic Acid)
Maslinic acid (Crataegus pinnatifida, extract) (standardized to contain 10% maslinic acid)
Maslinic acid in skin care cosmetics
Maslinic acid can be found in many cosmetic formulas due to its antioxidant and anti-inflammatory effects.
As an antioxidant, maslinic acid provides free radical fighting properties that aid in protecting and repair skin by deeply penetrating the dermal layers.
Maslinic acid works as a powerful skin regenerator and is good at preventing future breakouts and healing those that have already occurred.
Maslinic Acid counteracts inflammation to help reduce redness & irritation while protecting skin against oxidative stress.
Maslinic acid works well with hyaluronic acid to moisture your skin and vitalizes your skins.
Maslinic acid as an effective anticancer agent
Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. Maslinic Acid becomes increasingly popular as more convincing anti-cancer results come out.
The most promising finding of the present study was the ability of maslinic acid to induce apoptosis in colonic cancer cells. It increased the activity of caspase-3 in a time and a dose-dependent manner, with the highest activation of 70-fold above that in control cells at a concentration of 250mmol/l.
Maslinic acid side effects
No adverse effects of maslinic acid have ever been reported yet. Maslinic acid is extracted naturally from Loquat leaves or olive fruits, both sources are healthy and safe.
Maslinic acid dosage
Maslinic acid is usually stacked with other ingredients, separate dosing information is not certain.
Always consult your doctor before taking maslinic acid in any forms.
Where to buy bulk Maslinic acid powder?
Cima Science is among the first manufacturers of maslinic acid powder in China.
Specifcations such as maslinic acid 10%, 20%, 30%, 50%, 70%, 98% are all available upon your request.
In addition, bulk oleanolic acid powder, ursolic acid powder from loquat leaf extract are also available from Cima Science Co., Ltd.
The package is 25kg/drum.
If you want to know the pricing and get the COA, specification sheet or other technical documents, just feel free to send an inquiry to us, and we will reply to you within 8 hours.
- Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells.
- Assessment of the safety of maslinic acid, a bioactive compound from Olea Europaea L
- Biological Activities of Extracts from Loquat (Eriobotrya japonica Lindl.) A Review
- Maslinic acid derived from olive fruit in combination with resistance training improves muscle mass and mobility functions in the elderly
- Maslinic Acid Enhances Immune Responses in Leukemic Mice Through Macrophage Phagocytosis and Natural Killer Cell Activities In Vivo
- Maslinic Acid, a Natural Phytoalexin-Type Triterpene from Olives — A Promising Nutraceutical
- Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation
- The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism
- The Potential of Triterpenoids from Loquat Leaves (Eriobotrya japonica) for Prevention and Treatment of Skin Disorder