What is D-(−)-Pantolactone?
D-(−)-Pantolactone is a degraded product of pantothenic acid, which is an essential vitamin that is water-soluble.
Product Name | D-(−)-Pantolactone powder |
Other names | Pro-vitamin B5; 2(3H)-Furanone; (R)-(-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone; D-(-)-2-Hydroxy-3,3-dimethyl-γ-butyrolactone; D-(-)-Pantoyl Lactone; Pantothenic Lactone; α-hydroxy-β,β-dimethyl-γ-butyrolactone; (3R)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone |
CAS Number | 599-04-2 |
Molecular Formula | C6H10O3 |
Molecular Weight | 130.14 |
Specifications | >98.0% |
Appearance | White Crystalline Powder |
Usage | Intermediate for the synthesis of pantothenic acid, |
Bulk Package | 25kg/drum |
The unique CAS Registry Number of D-(−)-Pantolactone is 599-04-2, with C6H10O3 as its molecular formula. It has many other names, such as α-hydroxy-β,β-dimethyl-γ-butyrolactone, Pantothenic Lactone, and its IUPAC Name is (3R)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone.
D-(−)-Pantolactone is hygroscopic and obtained by benzene/petroleum ether or sublimation. Its melting point is 80 (92°C), boiling point 130°C/2.4kPa, soluble in water, ethanol, ether, chloroform, carbon disulfide, benzene. r-type melting point is at 92°C, [α]-50.7° (C=2.05, H2O), s-type melting point is at 91°C, [α]+50° (C=2.00, H2O).
Manufacturing Process
D-(−)-Pantolactone is produced by condensation of isobutyraldehyde with formaldehyde to produce α,α-dimethyl-β-hydroxypropionaldehyde, which is further condensed and hydrolyzed, acidified and lactonized with the participation of calcium chloride.
D-(−)-Pantolactone Uses
It is used in the synthesis of calcium D-pantothenate, D-panthenol, Vitamin B5, or as other pharmaceutical intermediates.
Where to buy D-(−)-Pantolactone in bulk?
Cima Science is a professional manufacturer of D-(−)-Pantolactone powder in China. If you want to buy D-(−)-Pantolactone in large quantity, please send an inquiry to us to get the best quotation within 8 hours.