Dihydroberberine, a metabolite of berberine, is a highly bioavailable form of the berberine compound. It is called the super berberine, and research indicates that dihydroberberine powder is up to five times more effective than a standard berberine dietary supplement.
Here is the Dihydroberberine structure:

Why Dihydroberberine is better than berberine?
- Dihydroberberinebioavailability- Proven to be 5x more potent than regular berberine supplement, “Puls Berberine” harnesses the power of Glucose Dominant Dihydroberberine to deliver 5x the bioactive benefits of regular berberine.
- 2x longer-lasting (8 hours vs 4 hours)
- Lower dosages (cost-effective)
- Fewer side effects
- Better results and fewer side effects at a lower dose
- Eliminate digestive upset that can occur with regular berberine
Dihydroberberine Specifications
- Dihydroberberine 99% powder
- Dihydroberberine sulfate 99% powder
- Dihydroberberine hydrochloride 99% powder
We can find Dihydroberberine supplements on many shopping websites, such as Dihydroberberine capsules on Amazon. Like Genius brand dihydroberberine supplement, best dihydroberberine supplement. As the most mainstream specification in the market, Dihydroberberine 99% powder has the highest formulation applicability and usage rate. The other two forms of DHB are used almost exclusively in research and development pathways. Here is Cima’s Dihydroberberine 99% powder information:
Package (1kg/bag, 25kg/drum)
Shipment (by Courier like FedEx, UPS, by air, by sea)
USA Warehouse: IF you are in the USA, you can offer to ship from our CA warehouse, so you don’t have to deal with any customs and FDA matters. At present, Cima Science only opens offices in the United States. Countries other than the United States need to consider customs clearance ability. Of course, if FedEx and another express send it, they will act as customs agents until it is delivered to your door.
DHB Manufacturing Process
The manufacturing process of Dihydroberberine ensures the highest-quality standards, prioritizing quality and purity at every step. A commercially available brand of Dihydroberberine undergoes rigorous third-party testing to confirm that it meets strict specifications, including being 98% pure. The process adheres to gluten-free protocols, ensuring the final product is safe for many consumers. Advanced extraction and purification techniques produce only the purest form of Dihydroberberine, guaranteeing optimal potency and effectiveness.
Dihydroberberine Benefits
Dihydroberberine, a hydrogenated derivative of berberine, offers superior metabolic support by enhancing metabolism and supporting healthy blood sugar levels. As an AMPK activator, it helps improve body composition by driving carbohydrates to muscle rather than fat, making it 5x more effective than berberine. Dihydroberberine’s increased absorption boosts its concentration in the serum, with studies showing a 100mg dose achieving higher plasma concentrations than 500mg of Berberine. This improved absorption and sustained release support better insulin sensitivity, promoting efficient protein metabolism and optimal blood sugar regulation. With its potent effects and superior bioavailability, Dihydroberberine is a powerful extract for those seeking to support healthy metabolic function.
Dihydroberberine Dosage
The standard dose of Dihydroberberine typically ranges from 100 mg to 200 mg daily, depending on individual needs. With significantly higher bioavailability than berberine (BBR), Dihydroberberine is more efficiently absorbed by the body, allowing for greater effectiveness at lower doses. While 500 mg of berberine may be required to achieve similar plasma concentrations, only 100 mg of Dihydroberberine is needed due to its superior absorption. This higher bioavailability ensures that a smaller amount is effective, reducing potential issues with the low bioavailability often associated with berberine HCl and improving its impact on lipid metabolism and overall metabolic support.
Where to buy Dihydroberberine powder in bulk?
Wuxi Cima Science Co., Ltd is China’s bulk dihydroberberine powder manufacturer with its own factories in Wuxi and Shandong Province. The annual production capacity is more than 100 tons, and there is spot supply all year round. (Certificate of Analysis COA and other technical documents like MOA, MSDS, and other certificates are available)
Cima Science focuses on high-quality standards. HPLC or GC will conduct all purity and content assays according to the product characteristics to ensure that physical, chemical, and microbiological specifications are controlled to meet the requirements of the FDA or EU. If you are a dihydroberberine distributor and supplier in the USA interested in wholesale dihydroberberine or want to try to use it in your new formula, please contact Cima’s team, and we will feed back your quality documents and quotation within 24 hours.







